Purine nucleoside analogs have unique and broad-spectrum curative effects. Various purine structural analogs that mimic the endogenous nucleosides are designed to target the main steps in the cellular metabolism. Purine nucleosides have integrated importance with the other classes of antimetabolites, pyrimidines [1], and antifolates [1,2]. Thus
Purine analog antimetabolites include thiopurines, deoxypurines, arabinose purine analogs, and base-modified purine nucleosides [].Although thiopurines were introduced into the clinic in the early era of cancer chemotherapy, few representative drugs are known.
purine analog–based treatments had been stopped early on the basis drugs. References. 1. U.S. Food and Drug Administration
Anti-Viral drugs. Many antiviral drugs are Purine or Pyrimidine analogs. Many antiviral drugs are Prodrugs. They must be phosphorylated by viral or
Drugs. This page cannot be displayed because your browser has been configured Antimetabolites, Folate Analogs; Antimetabolites, Purine Analogs
Tadmor, Purine analog toxicity in patients with hairy Spurgeon, Cladribine: not just another purine analogue?, Expert Opin Investig Drugs, № 18, с.
Answer to Solved In what way are purine analog chemotherapy drugs and
by A Dhainaut 2024 Cited by 87A series of 36 purine and purine analog derivatives have been synthesized and tested for their ability to modulate multidrug resistance in
Valacyclovir is an antiviral drug that belongs to the purine (guanine) nucleoside analog drug class.¹. As a prodrug to acyclovir (Zovirax)
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