The IL-23 drugs target the p19 gene which has been directly linked to psoriasis and that may give them a competitive advantage over the IL-17 and TNF biologics that work through other pathways. But the IL-17 inhibitors have surpassed the IL-23 inhibitors in a different way.
IL-17 inhibitors are another class of biologic medications approved for spondyloarthritis. There are currently two IL-17 inhibitors approved by the FDA for
IL-23 inhibitors such as Guselkumab, Tildrakizumab, and IL-12/-23 inhibitor Ustekinumab are a relatively newer class of drugs that have shown effectiveness in treating PsA. IL-23 and IL-17 inhibitors show similar efficacy at 1 year and over, however, when it comes to rapid response rate, IL-17 inhibitors are superior.
Background and Objective The most recently approved biologics for moderate-to-severe psoriasis are the interleukin (IL)-17 and IL-23 inhibitors. Drug survival is a frequently used outcome to assess drug performance in practice. An overview of the available drug survival studies regarding IL-17 and IL-23 inhibitors is lacking. Therefore, our objective was to assess the drug survival of IL-17
There are a dozen biologic medications for psoriasis, which fall into categories (IL-17 inhibitors, IL-23 inhibitors, and TNF-alpha inhibitors)
There are a dozen biologic medications for psoriasis, which fall into categories (IL-17 inhibitors, IL-23 inhibitors, and TNF-alpha inhibitors)
IL-23 inhibitors such as Guselkumab, Tildrakizumab, and IL-12/-23 inhibitor Ustekinumab are a relatively newer class of drugs that have shown effectiveness in treating PsA. IL-23 and IL-17 inhibitors show similar efficacy at 1 year and over, however, when it comes to rapid response rate, IL-17 inhibitors are superior.
Background and Objective The most recently approved biologics for moderate-to-severe psoriasis are the interleukin (IL)-17 and IL-23 inhibitors. Drug survival is a frequently used outcome to assess drug performance in practice. An overview of the available drug survival studies regarding IL-17 and IL-23 inhibitors is lacking. Therefore, our objective was to assess the drug survival of IL-17
Introduction. The three approved IL-17 inhibitors consist of IL-17A inhibitors (secukinumab and ixekizumab) and an IL-17 receptor (IL-17R) inhibitor (brodalumab)
Comments
dit-il. il a dit
dit-il. J'ai dit.
dit-il. dit Jane,
dit-il. Dis-je
en pagaille et je dois admettre que c'est très agacent à lire. J'ais bien aimé ce chapitre mais la lecture à été un calvaire.